Endoform® Antimicrobial Is an extracellular matrix which supports all phases of healing. It contains:
Natural intact collagen scaffold
Secondary molecules that are important during healing
Only natural tissue components
Endoform® Antimicrobial is a natural collagen scaffold with 0.3% ionic silver to protect it from microbial colonisation. Benefits include:
Minimal impact on cell viability
Provides extended antimicrobial protection for up to 7 days
Has a wide spectrum of antimicrobial protection
Products
Endoform® Antimicrobial Dermal Template is an advanced wound care dressing primarily composed of natural, non-reconstituted collagen retaining the native extracellular matrix associated macromolecules including fibronectin, glycosaminoglycans, laminin, and elastin.
Endoform® Antimicrobial Dermal Template contains approximately 12 pg/cm2 (-0.3% w/w) ionic silver, intended to inhibit colonisation of the dressing. The dressing is effective against a broad spectrum of microbes, including Acinetobacter baumannii, Candida albicans, Candida parapsilosis, Candida glabrata, Escherichia coli, Methicillin Resistant Staphylococcus aureus (MRSA), coagulase negative Staphylococci, group A (beta-hemolytic) Streptococci, Pseudomonas aeruginosa, Aspergillus niger; and Vancomycin Resistant Enterococci (VRE). The dressing provides sustained antimicrobial effectiveness within the dressing for up to 7 days.
Overbeck, N., G. M. Nagvajara, S. Ferzoco, B. C. H. May, A. Beierschmitt and S. Qi (2020). “In-vivo evaluation of a reinforced ovine biologic: a comparative study to available hernia mesh repair materials.” Hernia |full-text available|
How to apply Endoform® Natural and Endoform® Antimicrobial
Endoform® Mechanism of Action – Protease Modulation
Endoform® extracellular matrix (ECM) stays intact in the wound bed to help provide visual cues to wound healing and modulate unbalanced wound proteases. This animation describes how Endoform® works in the wound bed to assist with wound healing and help build new tissue.
Endoform® Application in Pediatrics
Watch as Dr. Amaya (Pediatric Wound Care & Laser Specialists, Houston, Texas) demonstrates the proper use of Endoform® to dress and protect a child’s wounds. This dermal template helps wounds heal and close, as well as help grow new skin over your child’s wound.
Clinical Resource Library
NEW RESOURCE – Using Endoform® to Escape the Inflammatory Phase Earlier
Chronic wounds are characterized by elevated wound proteases and high bioburden which limits healing and traps wounds in the inflammatory phase. The following Clinical Resource shows how Endoform® can be used to help wounds escape the inflammatory phase.
Skin is composed of cells and extracellular matrix (ECM). The ECM is an essential tissue component that supports cells and directs important cell processes. In wounds, tissue ECM is missing or damaged, and Endoform® ECM technology can be used to replace the missing ECM. This clinical resource provides an overview of the science of ECM, its function and composition and how Endoform® can be used during all phases of healing to build tissue.
Product claims relating to MMP modulation and biofilm prevention are subject to local regulatory approval. Consult with your local representative for more information.
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To learn more about Endoform Antimicrobial, contact your local Appulse representative or call 1-860-337-7730